Groupe d'Etude en Oncologie du Quebec

Titre	Pelvic Nodes Ultra-Hypo Fractionated Versus Conventionally Fractionated IMRT With HDR Brachytherapy Boost in Prostate Cancer: A Collaborative Multi-institutional Non-inferiority Phase 3 Trial.
Protocole ID	PCS-XI
ClinicalTrials.gov ID	NCT05820633
Type(s) de cancer	Prostate
Phase	Phase III
Type étude	Clinique
Institution	CIUSSS DE L'EST-DE-L'ILE-DE-MONTREAL PAV. MAISONNEUVE/PAV. MARCEL-LAMOUREUX 5415 boul. de l'Assomption, Montréal, QC, H1T2M4
Ville	Montréal
Investigateur(trice) principal(e)	Dr Peter Vavassis
Coordonnateur(trice)	Lys Fernet 514-252-3400 poste 3227
Statut	Actif en recrutement
Date d'activation	11-05-2023
Critètes d'éligibilité	Histopathologically confirmed adenocarcinoma of the prostate. All clinical stages with lymph node involvement risk needing pelvis RT. Stage Mx or M0. Unfavorable Intermediate, high or very high-risk disease according to NCCN guidelines. Having the ability to give free and informed consent.
Critètes d'exclusion	Clinical stage M1. IPSS Score > 20 with alpha-blocking medication. Prior pelvic radiotherapy, History of active collagenosis (Lupus, Scleroderma, Dermatomyositis). Past history of Inflammatory Bowell Disease. Bilateral hip prosthesis.

Groupe d'étude en oncologie du Québec